1498 Results found
Articles
High Cervical Intrathecal Targeted Drug Delivery for Refractory Neuropathic Craniofacial Pain
Abstract Objectives: Neuropathic craniofacial pain syndromes are heterogeneous with regards to clinical presentation and etiology. As such, they pose a diagnostic and management challenge, and are often refractory to medical and interventional management. High...
Journal:
NeuromodulationPublished:
July 4, 2025The Effectiveness of Noninvasive Brain Stimulation Techniques Combined With Motor Interventions in Adult Patients After Stroke: An Overview of Systematic Reviews
Abstract Objective: This study aimed to provide an overview of systematic reviews (SRs) about the effectiveness of combining noninvasive brain stimulation (NIBS) techniques with rehabilitation in adult patients with stroke. Materials and methods: The...
Journal:
NeuromodulationPublished:
July 4, 2025The Effect of Transcutaneous Trigeminal Nerve Stimulation and Transcutaneous Auricular Vagal Nerve Stimulation on the Biomarker Response to Stress
Abstract Background: Transcutaneous trigeminal nerve stimulation (tTNS) and transcutaneous auricular vagal nerve stimulation (tVNS) are neurostimulation methods that have recently gained attention for their potential to modify the response to stress. However, current understanding...
Journal:
NeuromodulationPublished:
July 4, 2025Abdominal Vagus Nerve Stimulation Increases Firing in the Rat Locus Coeruleus
Abstract Background: Cervical vagus nerve stimulation (VNS) is a clinically available treatment for refractory epilepsy and depression. Animal studies show that electrical activation of the noradrenergic brain region, locus coeruleus (LC), is essential for...
Journal:
NeuromodulationPublished:
June 27, 2025Caregivers’ Perspectives and Decision-Making on Deep Brain Stimulation in GNAO1-Related Disorders
Abstract Objectives: Deep brain stimulation (DBS) is an advanced treatment for individuals with GNAO1-related disorders (GNAO1-RD), which are characterized by severe movement abnormalities such as status dystonicus and dyskinetic crises. Decision-making surrounding DBS is...
Journal:
NeuromodulationPublished:
June 27, 2025Transcutaneous Cervical Vagus Nerve Stimulation Modulates Prefrontal Cortex Activity During Opioid Withdrawal in Individuals With Opioid Use Disorder
Abstract Background: Opioid use disorder (OUD) is associated with considerable morbidity and mortality with limited treatment approaches. Understanding brain mechanisms in response to treatment could be useful in guiding future developments in treatment approaches....
Journal:
NeuromodulationPublished:
June 27, 2025Does Greater Occipital Nerve Block Modulate Brainstem Excitability? Insights From a Randomized Controlled Study in Migraine
Abstract Objectives: Greater occipital nerve block (GONb) is widely used in the treatment of migraine; however, its effects on brainstem excitability remain unclear. This study aimed to assess whether GONb alters brainstem excitability in...
Journal:
NeuromodulationPublished:
June 20, 2025Comparison of Two Methods of Deep Brain Stimulation Lead Reconstruction and Their Prediction Capacities
Abstract Objectives: Deep brain stimulation (DBS) technology has become increasingly advanced, and tools capable of optimizing programming are necessary. Three-dimensional (3D) electrode imaging reconstruction has the potential to assist clinicians in selecting the most...
Journal:
NeuromodulationPublished:
June 20, 2025Adaptive vs Conventional Deep Brain Stimulation of the Subthalamic Nucleus for Treatment of Parkinson’s Disease: A Multicenter Retrospective Study
Abstract Objectives: Conventional deep brain stimulation (cDBS) is an established treatment for Parkinson’s disease (PD), whereas adaptive DBS (aDBS) represents a promising approach with potential advantages in minimizing stimulation-induced side effects and enhancing quality...
Journal:
NeuromodulationPublished:
June 13, 2025Optimization Simulations of Transcranial Direct Current Stimulation Montages in Children With Perinatal Stroke
Abstract Background: Perinatal stroke (PS) is a vascular brain injury that causes most hemiparetic cerebral palsy. Transcranial direct current stimulation (tDCS) applies a weak electric field (EF) to the scalp, and targeting motor cortex...
Journal:
NeuromodulationPublished:
June 13, 2025Systematic Review and Meta-Analysis of Bilateral Centromedian Nucleus Neuromodulation for Multifocal and Generalized Epilepsy
Abstract Objectives: Generalized and multifocal forms of drug-resistant epilepsy are highly prevalent but have limited treatment options. Centromedian nucleus (CMN) thalamic neuromodulation has emerged as an effective treatment for these epilepsies, but head-to-head neuromodulation...
Journal:
NeuromodulationPublished:
June 13, 2025Systematic Review to Identify Patient-Level Predictors of Treatment Response to Spinal Cord Stimulation for Neuropathic Pain for Studies Published From 2012 to 2024
Abstract Objective: Chronic neuropathic pain is challenging to manage, but one recommended treatment is spinal cord stimulation (SCS), which may provide pain relief and improvements in physical function and health-related quality of life. Almost...
Journal:
NeuromodulationPublished:
June 6, 2025The Impact of Spinal Cord Stimulation on Patients’ Ability to Work and Work-Related Outcomes
Abstract Introduction: Chronic low back pain is one of the most common causes of absence from work. This not only has economic consequences but also affects the mental health of patients. Furthermore, returning to...
Journal:
NeuromodulationPublished:
June 6, 2025Preclinical Insights Into the Effects of Frequency and Pulse Width on Evoked Compound Action Potential Morphology During Spinal Cord Stimulation
Abstract Objectives: High-frequency spinal cord stimulation (SCS) at 1000 Hz was shown to reduce evoked compound action potential (ECAP) amplitude, likely owing to asynchronous firing of dorsal column (DC) axons. To investigate the relationship...
Journal:
NeuromodulationPublished:
June 6, 2025Jeffrey Ardell, PhD (December 20, 1952-February 12, 2025)
Journal:
NeuromodulationPublished:
June 6, 2025Theta-Burst Stimulation of the Right Temporoparietal Junction and Implicit Theory of Mind in Autism
Abstract Objectives: Theory of mind (ToM), or mentalizing, is the ability to attribute mental states to oneself and others and is altered in individuals with autism spectrum disorder (ASD). Recent evidence suggests that implicit...
Journal:
NeuromodulationPublished:
May 30, 2025Best Practice Guidelines for Neuromodulation in Pain Management: Insight From the Neuromodulation Society of Australia and New Zealand
Abstract Objectives: The Neuromodulation Society of Australia and New Zealand (NSANZ) developed evidence-based best practice guidelines for spinal cord stimulation (SCS) in chronic pain management. The primary objective was to provide clear guidance to...
Journal:
NeuromodulationPublished:
May 30, 2025
