1446 Results found
Articles
Noninvasive Vagus Nerve Stimulation in Parkinson’s Disease: A Systematic Review
Abstract Background: While pharmacologic interventions remain the mainstay of Parkinson’s disease (PD) treatment, alternative approaches such as vagus nerve stimulation (VNS) have drawn attention for their potential in managing PD symptoms. Objective: We aimed...
Journal:
NeuromodulationPublished:
March 14, 2025A First-In-Human Feasibility Study of a New Implantable Tibial Nerve Stimulator for Overactive Bladder Syndrome
Abstract Objectives: This study aimed to evaluate the preliminary feasibility and safety of a new implantable tibial nerve stimulator device in patients with overactive bladder (OAB). Materials and methods: Ten patients with OAB in...
Journal:
NeuromodulationPublished:
March 7, 2025Pulsed Shortwave (Radiofrequency) Therapy With a Noninvasive, Wearable, Disposable Device: A Randomized, Participant- and Assessor-Masked, Sham-Controlled Pilot Study
Abstract Objectives: Pulsed shortwave therapy (PSWT) is a nonpharmacologic/noninvasive modality that may offer analgesic benefits without notable side effects or complications. This pilot study aimed to assess the feasibility of a PSWT protocol and...
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NeuromodulationPublished:
February 28, 2025Pulsed Shortwave (Radiofrequency) Therapy With a Noninvasive, Wearable, Disposable Device: A Randomized, Participant- and Assessor-Masked, Sham-Controlled Pilot Study
Abstract Objectives: Pulsed shortwave therapy (PSWT) is a nonpharmacologic/noninvasive modality that may offer analgesic benefits without notable side effects or complications. This pilot study aimed to assess the feasibility of a PSWT protocol and...
Journal:
NeuromodulationPublished:
February 28, 2025Safety and Effectiveness of Multisite Transcutaneous Spinal Cord Stimulation Combined With Activity-Based Therapy When Delivered in a Community Rehabilitation Setting: A Real-World Pilot Study
Abstract Objective: The primary aim of this study was to preliminarily evaluate the safety and efficacy of multisite transcutaneous spinal cord stimulation (tSCS) combined with activity-based therapy (ABT) in individuals with chronic spinal cord...
Journal:
NeuromodulationPublished:
February 28, 2025Phase-Amplitude Coupling in Response to Transcutaneous Vagus Nerve Stimulation: Focus on Regions Implicated in Mood and Memory
Abstract Objective: This study aimed to investigate whether transcutaneous vagus nerve stimulation (tVNS) at different frequencies affects phase-amplitude coupling among regions of the brain linked to mood and memory disorders using simultaneous magnetoencephalography (MEG)...
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NeuromodulationPublished:
February 28, 2025Phase-Amplitude Coupling in Response to Transcutaneous Vagus Nerve Stimulation: Focus on Regions Implicated in Mood and Memory
Abstract Objective: This study aimed to investigate whether transcutaneous vagus nerve stimulation (tVNS) at different frequencies affects phase-amplitude coupling among regions of the brain linked to mood and memory disorders using simultaneous magnetoencephalography (MEG)...
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NeuromodulationPublished:
February 28, 2025Response to: YouTube as a Source of Medical Information About Peripheral Nerve Stimulation
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NeuromodulationPublished:
February 28, 2025Effects of Auricular Stimulation on Inflammatory Parameters: Results of a Systematic Review and Meta-Analysis of Randomized Controlled Trials
Abstract Background: The number of randomized controlled trials (RCTs) using auricular stimulation (AS) techniques, such as transauricular vagus nerve stimulation, auricular electrostimulation, auricular acupuncture, and acupressure in experimental and clinical settings has increased markedly...
Journal:
NeuromodulationPublished:
February 28, 2025Comparison of Two Different Neuromodulation Treatments in Patients With Acute Zoster-Related Trigeminal Neuropathic Pain and Pain Catastrophizing
Abstract Objective: This study aimed to compare the efficacy of two neuromodulation techniques, peripheral nerve stimulation (PNS) and pulsed radiofrequency (PRF), in patients with acute zoster-related trigeminal neuropathic pain with pain catastrophizing. Materials and...
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NeuromodulationPublished:
February 21, 2025Electroacupuncture at ST36 Relieves Visceral Hypersensitivity Based on the Vagus-Adrenal Axis in the Remission Stage of Ulcerative Colitis
Abstract Background and aims: Although electroacupuncture (EA) at ST36 has been shown to alleviate visceral hypersensitivity in rats with ulcerative colitis (UC), the exact mechanism remains unknown. This study aims to investigate whether EA...
Journal:
NeuromodulationPublished:
February 21, 2025Incidence of Lead Tip Fracture and Retention After Percutaneous Lead Implantation for Peripheral Nerve Stimulation With an External Pulse Generator: A Multicenter Comparative Analysis of 456 Lead Implants Across Two Lead Hardware Generations
Abstract Objectives: Lead fracture and retention are potential adverse events that can occur after peripheral nerve stimulator (PNS) lead implantation, although recent technologic advancements in PNS hardware have been implemented to avert this risk....
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NeuromodulationPublished:
February 21, 2025Is There a Correlation Between Objective Measurement Tools and Self-Reporting Questionnaires To Evaluate Physical Activity and Health Status in Patients With Persistent Spinal Pain Syndrome Type 2 Before and After Spinal Cord Stimulation? Outcomes of a Feasibility Study
Abstract Introduction: The effect of spinal cord stimulation (SCS) on physical activity in patients with persistent spinal pain syndrome (PSPS) type 2 is commonly evaluated with standardized, validated self-reporting questionnaires. However, questionnaires are susceptible...
Journal:
NeuromodulationPublished:
February 21, 2025Timing Matters: Preconditioning Effects of Cathodal Transcranial Direct Current Stimulation on Intermittent Theta-Burst Stimulation-Induced Neuroplasticity in the Primary Motor Cortex
Abstract Background: Recent advances have highlighted the interplay between intermittent theta-burst stimulation (iTBS) and transcranial direct current stimulation (tDCS) in neuroplasticity modulation. However, the synergistic potential of these modalities in optimizing plasticity, particularly with...
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NeuromodulationPublished:
February 21, 2025Development of an Educational Curriculum for Implanting and Managing Vagus Nerve Stimulators for Epilepsy
Abstract Background: Vagus nerve stimulation (VNS) devices are commonly used for extracranial neuromodulation of drug-resistant epilepsy. These devices are implanted by multiple surgical subspecialties and managed by practitioners with varying levels of epilepsy-specific expertise....
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NeuromodulationPublished:
February 21, 2025Tonic and Event-Related Phasic Transcutaneous Auricular Vagus Nerve Stimulation Alters Pupil Responses in the Change-Detection Task
Abstract Background: Transcutaneous auricular vagus nerve stimulation (taVNS) has emerged as a potential modulator of cognitive behavior that activates the locus coeruleus-noradrenaline (LC-NA) system. Previous studies explored both phasic and tonic taVNS by investigating...
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NeuromodulationPublished:
February 14, 2025Effect and Mechanism of Vagal Nerve Stimulation on Gastric Motility: A Preliminary Rodent Study
Abstract Background: Patients with functional dyspepsia often exhibit gastrointestinal motor disorders associated with gastric myoelectrical dysrhythmia. This study investigated the effects of vagal nerve stimulation (VNS) in a rodent model of gastric slow-wave dysrhythmia...
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NeuromodulationPublished:
February 7, 2025Delay- and Pressure-Dependent Neuromodulatory Effects of Transcranial Ultrasound Stimulation
Abstract Objective: Despite the growing interest in transcranial focused ultrasound stimulation (TUS), our understanding of its underlying mechanisms remains limited. In this study, we aimed to investigate the effects of TUS on several functional...
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NeuromodulationPublished:
February 7, 2025A Clinical Care Pathway for Patients With Chronic Mechanical Low Back Pain Having Restorative Neurostimulation for Multifidus Muscle: Description, Patient Compliance, Clinical Outcomes, and Satisfaction in the First Two Years
Abstract Objectives: Restorative neurostimulation for multifidus muscle is a novel therapy for chronic low back pain (CLBP). Optimal outcomes require interdisciplinary follow-up. We describe a clinical care pathway (CPW) for this therapy and report...
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NeuromodulationPublished:
January 24, 2025Accelerative Effects of Transcutaneous Electrical Acustimulation on Postoperative Recovery After Thoracolumbar Vertebral Fracture Associated With Suppressed Sympathetic Activity and Interleukin-6
Abstract Objectives: Gastrointestinal (GI) disturbance is a frequent complication in patients with thoracolumbar vertebral fracture (TVF). Transcutaneous electrical acustimulation (TEA) has been reported to effectively accelerate postoperative GI function recovery after abdominal surgery. This...
Journal:
NeuromodulationPublished:
January 17, 2025
