Let’s Get Personal: Using Genetic and Environmental Factors to Guide Pain Treatment
Dr. Roger Fillingim discusses the value of a comprehensive approach to personalized medicine. After discussing the value of CYP2D6 genotyping to predict opioid efficiency, he shows that drug interactions drive CYP2D6 phenoconversion in some patients, proving that a purely genomic approach to precision medicine is insufficient.
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Using published data, he broadens the scope of personalized medicine to include non-genetic factors based on his biopsychosocial model of pain.
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