Experts

Dominic Hegarty

MD
(Ireland)

Dominic Hegarty

MD
(Ireland)

Biography
Biography

Dominic Hegarty
BSc., BMedSc., MB., MSc., PhD. FCARSCI, FFPMCAI, FIPP


• Consultant in Pain Management & Neuromodulation, Mater Private Hospital, Cork
• Honorary Consultant Guy’s & St. Thomas’ Hospital, London

BIOGRAPHY

Dr. Hegarty is recognised as one of the country’s foremost interventional pain management doctors who is constantly developing new pain techniques to deal with the most complex cases in this area. He is the holder of a doctrine degree (Ph.D., UCC), Master of Science (MSc., Edinburgh) a Fellowships in Ireland, USA (FIPP) and London (Royal College of Medicine) in the area of Pain Management.

He has specialised in pain management over the last 2 decades and his expertise in this area is regularly sought by national media and in the High Court on medical legal matters. Dr. Hegarty has secured over €3 million in research grants and sponsorship over the last 3 years. He continues to collaborate with innovation centres and industry in order to provide the best solutions to help individuals who have to deal with chronic pain on a daily basis.

In addition to his teaching posts Dr. Hegarty was awarded the unique position of Horary Consultant in Guy’s & St. Thomas’ Hospital, London. He co-founded the division of Pain Medicine in the Department of Anaesthesia & Pain Medicine at Cork University Hospital and South Infirmary & Victoria Hospital, Cork. He served as a consultant for 8 years in the Health Service Executive ( HSE) before joining the Mater Private Hospital Cork.

More recently he was the winner of the 2017 Conference ambassador award for “Best International Medical Conference” by Failte Ireland.

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Lacrimal Gland Denervation Alters Tear Protein Composition and Impairs Ipsilateral Eye Closures and Corneal Nociception.

Hegarty DM1, David LL2, Aicher SA1.
Invest Ophthalmol Vis Sci. 2018 Oct 1;59(12):5217-5224. doi: 10.1167/iovs.18-25267.

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Cocaine Exposure Modulates Perineuronal Nets and Synaptic Excitability of Fast-Spiking Interneurons in the Medial Prefrontal Cortex.

Slaker ML1, Jorgensen ET2, Hegarty DM3, Liu X4, Kong Y4, Zhang F4, Linhardt RJ4, Brown TE2, Aicher SA3, Sorg BA1.
eNeuro. 2018 Oct 4;5(5). pii: ENEURO.0221-18.2018. doi: 10.1523/ENEURO.0221-18.2018. eCollection 2018 Sep-Oct.

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Acute hyperalgesia and delayed dry eye after corneal abrasion injury.

Hegarty DM1, Hermes SM1, Morgan MM2, Aicher SA1.
Pain Rep. 2018 Jun 20;3(4):e664. doi: 10.1097/PR9.0000000000000664. eCollection 2018 Jul-Aug.

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Abstracts from Proceedings Cork CRPS 2017: IASP Special Interest Group in Complex Regional Pain Syndrome (CRPS).

Hegarty D.
Pain Rep. 2018 Jan 19;3(1):e635. doi: 10.1097/PR9.0000000000000635. eCollection 2018 Jan.

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Denervation of the Lacrimal Gland Leads to Corneal Hypoalgesia in a Novel Rat Model of Aqueous Dry Eye Disease.

Aicher SA, Hermes SM, Hegarty DM.
Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6981-9. doi: 10.1167/iovs.15-17497.

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Nipple discharge.

Labib PL1, Gallegos N2, Hegarty D3.
BMJ. 2015 Jul 21;351:h3123. doi: 10.1136/bmj.h3123.

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Capsaicin-responsive corneal afferents do not contain TRPV1 at their central terminals in trigeminal nucleus caudalis in rats.

Hegarty DM1, Hermes SM2, Largent-Milnes TM3, Aicher SA4.
J Chem Neuroanat. 2014 Nov;61-62:1-12. doi: 10.1016/j.jchemneu.2014.06.006. Epub 2014 Jul 1.

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Psychological Reactions and Persistent Facial Pain following Enucleation.

Hegarty D1, Coakley D2, Dooley I2.
Pain Res Treat. 2014;2014:232989. doi: 10.1155/2014/232989. Epub 2014 Apr 23.

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Physiological temperatures drive glutamate release onto trigeminal superficial dorsal horn neurons.

Largent-Milnes TM1, Hegarty DM2, Aicher SA2, Andresen MC2.
J Neurophysiol. 2014 Jun 1;111(11):2222-31. doi: 10.1152/jn.00912.2013. Epub 2014 Mar 5.

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Corneal pain activates a trigemino-parabrachial pathway in rats.

Aicher SA1, Hegarty DM2, Hermes SM3.
Brain Res. 2014 Mar 6;1550:18-26. doi: 10.1016/j.brainres.2014.01.002. Epub 2014 Jan 10.

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Corneal afferents differentially target thalamic- and parabrachial-projecting neurons in spinal trigeminal nucleus caudalis.

Aicher SA1, Hermes SM2, Hegarty DM3.
Neuroscience. 2013 Mar 1;232:182-93. doi: 10.1016/j.neuroscience.2012.11.033. Epub 2012 Nov 29.

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Multivariate prognostic modeling of persistent pain following lumbar discectomy.

Hegarty D1, Shorten G.
Pain Physician. 2012 Sep-Oct;15(5):421-34.

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Distribution of CB1 cannabinoid receptors and their relationship with mu-opioid receptors in the rat periaqueductal gray.

Wilson-Poe AR1, Morgan MM, Aicher SA, Hegarty DM.
Neuroscience. 2012 Jun 28;213:191-200. doi: 10.1016/j.neuroscience.2012.03.038. Epub 2012 Apr 19.

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Descending projections from the rostral ventromedial medulla (RVM) to trigeminal and spinal dorsal horns are morphologically and neurochemically distinct.

Aicher SA1, Hermes SM, Whittier KL, Hegarty DM.
J Chem Neuroanat. 2012 Mar;43(2):103-11. doi: 10.1016/j.jchemneu.2011.11.002. Epub 2011 Nov 20.

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Spinal cord stimulation: the clinical application of new technology.

Hegarty D1.
Anesthesiol Res Pract. 2012;2012:375691. doi: 10.1155/2012/375691. Epub 2011 Oct 5.

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Analgesic effect of bilateral ultrasound-guided pudendal nerve blocks in management of interstitial cystitis.

Lean LL, Hegarty D, Harmon D.
J Anesth. 2012 Feb;26(1):128-9. doi: 10.1007/s00540-011-1243-z.

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Peripheral nerve stimulation of the thoracic paravertebral plexus for chronic neuropathic pain.

Hegarty D1, Goroszeniuk T.
Pain Physician. 2011 May-Jun;14(3):295-300.

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A Randomised, Placebo-controlled Trial of the Effects of Preoperative Pregabalin on Pain Intensity and Opioid Consumption following Lumbar Discectomy.

Hegarty DA1, Shorten GD.
Korean J Pain. 2011 Mar;24(1):22-30. doi: 10.3344/kjp.2011.24.1.22. Epub 2011 Feb 25.

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Association between preoperative magnetic resonance imaging, pain intensity and quantitative sensory testing in patients awaiting lumbar diskectomy.

Hegarty D1, O'Connor OJ, Moore M, O'Regan KN, Shorten G, Maher MM.
J Med Imaging Radiat Oncol. 2011 Feb;55(1):4-10. doi: 10.1111/j.1754-9485.2010.02222.x.

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Differential localization of vesicular glutamate transporters and peptides in corneal afferents to trigeminal nucleus caudalis.

Hegarty DM1, Tonsfeldt K, Hermes SM, Helfand H, Aicher SA.
J Comp Neurol. 2010 Sep 1;518(17):3557-69. doi: 10.1002/cne.22414.

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Opioid receptor internalization contributes to dermorphin-mediated antinociception.

Macey TA1, Ingram SL, Bobeck EN, Hegarty DM, Aicher SA, Arttamangkul S, Morgan MM.
Neuroscience. 2010 Jun 30;168(2):543-50. doi: 10.1016/j.neuroscience.2010.04.003. Epub 2010 Apr 13.

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DNW–“did not wait” or “demographic needing work”: a study of the profile of patients who did not wait to be seen in an Irish emergency department.

Gilligan P1, Joseph D, Winder S, Keeffe FO, Oladipo O, Ayodele T, Asuquo Q, O'Kelly P, Hegarty D.
Emerg Med J. 2009 Nov;26(11):780-2. doi: 10.1136/emj.2008.063388.

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Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat.

Macey TA1, Bobeck EN, Hegarty DM, Aicher SA, Ingram SL, Morgan MM.
J Pharmacol Exp Ther. 2009 Nov;331(2):412-8. doi: 10.1124/jpet.109.152157. Epub 2009 Aug 14.

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The Transit/Admission Lounge study.

Gilligan P1, O'Kelly P, Hegarty D, Winder S.
Ir Med J. 2009 Jan;102(1):19-21.

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Periaqueductal gray neurons project to spinally projecting GABAergic neurons in the rostral ventromedial medulla.

Morgan MM1, Whittier KL, Hegarty DM, Aicher SA.
Pain. 2008 Nov 30;140(2):376-86. doi: 10.1016/j.pain.2008.09.009. Epub 2008 Oct 15.

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Inflammatory pain-induced signaling events following a conditional deletion of the N-methyl-D-aspartate receptor in spinal cord dorsal horn.

Cheng HT1, Suzuki M, Hegarty DM, Xu Q, Weyerbacher AR, South SM, Ohata M, Inturrisi CE.
Neuroscience. 2008 Aug 26;155(3):948-58. doi: 10.1016/j.neuroscience.2008.06.024. Epub 2008 Jun 19.

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Conditional deletion of the NMDA-NR1 receptor subunit gene in the central nucleus of the amygdala inhibits naloxone-induced conditioned place aversion in morphine-dependent mice.

Glass MJ1, Hegarty DM, Oselkin M, Quimson L, South SM, Xu Q, Pickel VM, Inturrisi CE.
Exp Neurol. 2008 Sep;213(1):57-70. doi: 10.1016/j.expneurol.2008.04.045. Epub 2008 May 20.

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The Boarders in the Emergency Department (BED) study.

Gilligan P1, Winder S, Singh I, Gupta V, Kelly PO, Hegarty D.
Emerg Med J. 2008 May;25(5):265-9. doi: 10.1136/emj.2007.048173.

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Why are we waiting? A study of the patients’ perspectives about their protracted stays in an emergency department.

Gilligan P1, Gupta V, Singh I, Winder S, O'Kelly P, Hegarty D.
Ir Med J. 2007 Nov-Dec;100(10):627-9.

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Kainate receptors are primarily postsynaptic to SP-containing axon terminals in the trigeminal dorsal horn.

Hegarty DM1, Mitchell JL, Swanson KC, Aicher SA.
Brain Res. 2007 Dec 12;1184:149-59. Epub 2007 Oct 4.

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Decreased substance P and NK1 receptor immunoreactivity and function in the spinal cord dorsal horn of morphine-treated neonatal rats.

Thomson LM1, Terman GW, Zeng J, Lowe J, Chavkin C, Hermes SM, Hegarty DM, Aicher SA.
J Pain. 2008 Jan;9(1):11-9. Epub 2007 Oct 24.

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Why Bazett’s formula?

Hegarty D.
Anesth Analg. 2007 Aug;105(2):535; author reply 536.

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SOCRATES Episode II (synopsis of Cochrane reviews applicable to emergency services Episode II): the return of Series III.

Gilligan P1, Pountney A, Wilson B, Mehigan C, Kidney E, Jennings P, Cooper J, Hegarty D, Lee J, Khan A, Lumsden G, Godden D, Shepherd M, Allonby-Neve L, Broderick A, Carr S, Wilson S, O' Sullivan J.
Emerg Med J. 2007 Jul;24(7):489-91.

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SOCRATES episode II (synopsis of cochrane reviews applicable to emergency services episode II): the return of the series II.

Gilligan P1, Lee J, Khan A, Jennings P, Cooper J, Hegarty D, Lumsden G, Godden D, Pountney A, Wilson B, Shepherd M, Allonby-Neve L, Mehigan C, Kidney E, Broderick A, Carr S, Wilson S, O'Sullivan J.
Emerg Med J. 2007 Feb;24(2):115-7.

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Tooth movement in the elderly: a case report.

Ryan W1, Hegarty D.
Gerodontology. 2006 Dec;23(4):242-4.

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Chronic postoperative pain and inguinal herniorrhaphy.

Hegarty D.
Br J Anaesth. 2006 Apr;96(4):538.

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Quick setup for light-cured bonding.

Hegarty D1, O'Leary I.
J Clin Orthod. 2005 Oct;39(10):612.

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SOCRATES 11 (synopsis of Cochrane Reviews applicable to emergency services).

Gilligan P1, Shepherd M, Lumsden G, Kitching G, Taylor A, Law H, Hegarty D, Khan A, Brenchley J, Jones J.
Emerg Med J. 2005 Sep;22(9):656-7.

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To lead or not to lead? Prospective controlled study of emergency nurses’ provision of advanced life support team leadership.

Gilligan P1, Bhatarcharjee C, Knight G, Smith M, Hegarty D, Shenton A, Todd F, Bradley P.
Emerg Med J. 2005 Sep;22(9):628-32.

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SOCRATES 10 (synopsis of Cochrane reviews applicable to emergency services).

Gilligan P1, Jones J, Khan A, Hegarty D, Shepherd M, Lumsden G, Kitching G, Taylor A, Law H, Brenchley J.
Emerg Med J. 2005 Aug;22(8):562-3.

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SOCRATES 9 (synopsis of Cochrane Reviews applicable to emergency services).

Gilligan P1, Hegarty D, Khan A, Shepherd M, Lumsden G, Kitching G, Taylor A, Law H, Brenchley J, Jones J.
Emerg Med J. 2005 Jul;22(7):510-1.

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SOCRATES 7 (synopsis of Cochrane Reviews applicable to emergency services).

Gilligan P1, Kitching G, Taylor A, Law H, Brenchley J, Jones J, Hegarty D, Khan A, Shepherd M, Lumsden G.
Emerg Med J. 2005 May;22(5):368-9.

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SOCRATES 6 (Synopsis of Cochrane Reviews applicable to emergency services).

Gilligan P1, Taylor A, Khan A, Jones J, Law H, Brenchley J, Hegarty D, Shepherd M, Lumsden G, Kitching G.
Emerg Med J. 2005 Apr;22(4):277-8.

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SOCRATES 5 (Synopsis of Cochrane Reviews applicable to Emergency Services).

Gilligan P1, Lumsden G, Jones J, Brenchley J, Hegarty D, Khan A, Shepherd M, Kitching G, Taylor A, Law H.
Emerg Med J. 2005 Mar;22(3):198-9.

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SOCRATES 4 (synopsis of Cochrane reviews applicable to emergency services).

Gilligan P1, Shepherd M, Lumsden G, Law H, Brenchley J, Kitching G, Taylor A, Khan A, Jones J, Hegarty D.
Emerg Med J. 2005 Feb;22(2):126-7.

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SOCRATES 3 (synopsis of Cochrane reviews applicable to emergency services).

Gilligan P1, Law H, Lumsden G, Brenchley J, Kitching G, Taylor A, Khan A, Shepherd M, Jones J, Hegarty D.
Emerg Med J. 2005 Jan;22(1):50-2.

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SOCRATES 2 (synopsis of Cochrane reviews applicable to emergency services).

Gilligan P1, Hegarty D, Khan A, Shepherd M, Lumsden G, Kitching G, Taylor A, Law H, Brenchley J, Jones J.
Emerg Med J. 2004 Nov;21(6):718-9.

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Are accident and emergency senior house officers getting slower?

Gilligan P, Illingworth RN, Crane S, Hegarty D.
Emerg Med J. 2004 Sep;21(5):646.

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SOCRATES 1 (synopsis of Cochrane reviews applicable to emergency services).

Gilligan P1, Khan A, Shepherd M, Lumsden G, Kitching G, Taylor A, Law H, Brenchley J, Jones J, Hegarty D.
Emerg Med J. 2004 Sep;21(5):584-5.

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A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain.

South SM1, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, Woolf CJ, Heinemann SF, Inturrisi CE.
J Neurosci. 2003 Jun 15;23(12):5031-40.

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The point of the needle. Occult pneumothorax: a review.

Gilligan P1, Hegarty D, Hassan TB.
Emerg Med J. 2003 May;20(3):293-6.

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A case report and review of the locked metacarpophalangeal joint.

Gilligan P1, Hegarty D, Bradley P, Todd F, Shenton AF.
Accid Emerg Nurs. 2003 Apr;11(2):103-5.

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Is lower incisor extraction treatment a compromise?

Hegarty DJ1, Hegarty M.
Dent Update. 1999 Apr;26(3):117-22.

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Presentations with Dentofacial Planner images.

Hegarty D1.
Am J Orthod Dentofacial Orthop. 1999 Jul;116(1):114-6.

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In defence of transplants: a case report.

Counihan DR1, Hegarty DJ.
Dent Update. 1997 May;24(4):138-42.

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Tetanus immunity in elderly people.

Murphy SM1, Hegarty DM, Feighery CS, Walsh JB, Williams Y, Coakley DP.
Age Ageing. 1995 Mar;24(2):99-102.

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Early post-tonsillectomy morbidity following hospital discharge: do patients and GPs know what to expect?

Kuo M1, Hegarty D, Johnson A, Stevenson S.
Health Trends. 1995;27(3):98-100.

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Inverted ductal papilloma of minor salivary glands.

Hegarty DJ1, Hopper C, Speight PM.
J Oral Pathol Med. 1994 Aug;23(7):334-6.

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Treatment of natal cleft sinus.

Hollingworth J, Hegarty DM, Kaufman HD.
BMJ. 1992 Aug 1;305(6848):311; author reply 311-2.

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