1311 Results found
Articles
NeuroDots: From Single-Target to Brain-Network Modulation: Why and What Is Needed?
Abstract Objectives: Current techniques in brain stimulation are still largely based on a phrenologic approach that a single brain target can treat a brain disorder. Nevertheless, meta-analyses of brain implants indicate an overall success...
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NeuromodulationPublished:
April 26, 2024Quantitative Sensory Testing in Spinal Cord Stimulation: A Narrative Review
Abstract Objectives: Quantitative sensory testing (QST) has been used for decades to study sensory abnormalities in multiple conditions in which the somatosensory system is compromised, including pain. It is commonly used in pharmacologic studies...
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NeuromodulationPublished:
April 26, 2024Case Series of Multicontact Peripheral Nerve Stimulation in the Transversus Abdominis Plane for Chronic Abdominal Wall Pain
Abstract Objectives: Managing abdominal pain can be difficult. This is due to the nonspecific nature of the pain, the multiple etiologies, and the different mechanisms underlying this type of pain. Abdominal wall pain in...
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NeuromodulationPublished:
April 12, 2024Long-term Efficacy of Bilateral Globus Pallidus Stimulation in the Treatment of Meige Syndrome
Abstract Objective: This study aimed to investigate the long-term efficacy and prognosis of bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) in patients with benign essential blepharospasm (BEB) and complete Meige syndrome, and...
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NeuromodulationPublished:
April 12, 2024Directional Deep Brain Stimulation in Parkinson’s Disease and Essential Tremor: A Retrospective Analysis
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NeuromodulationPublished:
April 5, 2024Response to: “Directional Deep Brain Stimulation in Parkinson’s Disease and Essential Tremor: A Retrospective Analysis”
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NeuromodulationPublished:
April 5, 2024Response to: “Directional Deep Brain Stimulation in Parkinson’s Disease and Essential Tremor: A Retrospective Analysis”
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NeuromodulationPublished:
April 5, 2024Short-term Dorsal Genital Nerve Stimulation Increases Subjective Arousal in Women With and Without Spinal Cord Injury: A Preliminary Investigation
Abstract Objectives: Female sexual dysfunction (FSD) affects an estimated 40% of women. Unfortunately, FSD is understudied, leading to limited treatment options for FSD. Neuromodulation has shown some success in alleviating FSD symptoms. We developed...
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NeuromodulationPublished:
April 5, 2024A Brief History of Slow Spinal Potentials, Gate Theory of Pain, and Spinal Cord Stimulation
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NeuromodulationPublished:
April 5, 2024Prospective Six-Month Analysis of Multiarea Burst Spinal Cord Stimulation: Correlating Intraoperative Neuromonitoring With Postoperative Programming and Clinical Outcomes
Abstract Introduction: DeRidder burst spinal cord stimulation (SCS) has shown superior relief from overall pain to traditional tonic neurostimulation therapies and a reduction in back and leg pain. However, nearly 80% of patients have...
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NeuromodulationPublished:
March 29, 2024Dorsal Root Ganglion Stimulation Relieves Chronic Neuropathic Pain Along With a Decrease in Cortical γ Power
Abstract Background: Stimulation of dorsal root ganglion (DRG) is an ideal neuromodulative intervention, providing pain relief in localized chronic pain conditions because γ-band oscillations reflect the intensity of ongoing chronic pain in patients affected....
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NeuromodulationPublished:
March 29, 2024Evaluation of Washout Periods After Dorsal Root Ganglion Stimulation Trial
Abstract Objective: Dorsal root ganglion stimulation (DRG-S) is a novel therapy to treat chronic pain. It has shown efficacy when delivered intermittently, suggesting a delayed washout effect exists. To measure the washout period, and...
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NeuromodulationPublished:
March 29, 2024Effects of Transcranial Ultrasound Stimulation on Blood Oxygen Metabolism and Brain Rhythms in Nitroglycerin-induced Migraine Mice
Abstract Objectives: In this study, we aimed to investigate the regulatory mechanism of transcranial ultrasound stimulation (TUS) on nitroglycerin-induced migraine in mice. Materials and methods: The experiment was divided into four groups, namely, the...
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NeuromodulationPublished:
March 22, 2024Effects of Transcranial Direct Current Stimulation on Clinical Outcomes, Calcitonin Gene-Related Peptide, and Pituitary Adenylate Cyclase-Activating Polypeptide-38 Levels in Menstrual Migraine
Abstract Objectives: Transcranial direct current stimulation (tDCS) has been suggested as an alternative treatment option for migraine. The present study aimed to evaluate the efficacy of tDCS on clinical outcomes in addition to calcitonin...
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NeuromodulationPublished:
March 22, 2024Frequency-Specific Effects of Noninvasive Median Nerve Stimulation on Gastric Slow Wave Activity in Humans
Abstract Objectives: The present study explored the effects of different frequencies of noninvasive median nerve stimulation (nMNS) on two autonomic responses: gastric slow waves under water-loading condition and heart rate variability (HRV). To the...
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NeuromodulationPublished:
March 15, 2024Five-Year Longitudinal Follow-up of Restorative Neurostimulation Shows Durability of Effectiveness in Patients With Refractory Chronic Low Back Pain Associated With Multifidus Muscle Dysfunction
Abstract Background: Adults with refractory, mechanical chronic low back pain associated with impaired neuromuscular control of the lumbar multifidus muscle have few treatment options that provide long-term clinical benefit. This study hypothesized that restorative...
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NeuromodulationPublished:
March 15, 2024Catheter Tip-Associated Mass With Continuous Infusion of Sufentanil for Persistent Spinal Pain Syndrome Type 2: A Case Report Including Histopathologic Examination and Review of the Associated Basic and Clinical Research
Abstract Objectives: Intrathecal opioids delivered by implanted pumps are used to treat malignant or nonmalignant chronic pain. In this study, we 1) review a case in which intrathecal infusions of sufentanil along with other...
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NeuromodulationPublished:
March 8, 2024Examining the Duration of Carryover Effect in Patients With Chronic Pain Treated With Spinal Cord Stimulation (EChO Study): An Open, Interventional, Investigator-Initiated, International Multicenter Study
Abstract Objectives: Spinal cord stimulation (SCS) is a surgical treatment for severe, chronic, neuropathic pain. It is based on one to two lead(s) implanted in the epidural space, stimulating the dorsal column. It has...
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NeuromodulationPublished:
March 8, 2024Spinal Cord Stimulation Trial Electrodes Rapidly Produce Epidural Scarring, Impeding Surgical Paddle Lead Placement
Abstract Objectives: After a successful percutaneous cylindrical electrode five-to-seven-day trial of spinal cord stimulation, subsequent permanent surgical paddle lead (SPL) placement can be impeded by epidural scar induced by the trial leads (TLs). Our...
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NeuromodulationPublished:
March 8, 2024Sequential Multilocus Repetitive Transcranial Magnetic Stimulation for Treatment of Tinnitus With and Without Comorbid Major Depressive Disorder
Abstract Objective: Repetitive transcranial magnetic stimulation (rTMS) is a promising treatment for tinnitus, although outcomes are highly variable. We previously described a multilocus sequential rTMS treatment protocol for tinnitus involving stimulation of both prefrontal...
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NeuromodulationPublished:
February 23, 2024
