848 Results found
Articles
Characterizing gaps in the preventive pharmacologic treatment of migraine: Multi-country results from the CaMEO-I study
Abstract Objective: To analyze data from the Chronic Migraine Epidemiology and Outcomes-International (CaMEO-I) Study in order to characterize preventive medication use and identify preventive usage gaps among people with migraine across multiple countries. Background:...
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May 10, 2024Suspension of Short-lasting, Unilateral, Neuralgiform headache attacks with Conjunctival injection and Tearing (SUNCT) symptoms with ayahuasca and serotonergic psychedelics
No abstract available Keywords: : ayahuasca; Short‐lasting Unilateral Neuralgiform headache attacks with Conjunctival injection and Tearing; psychedelics.
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May 10, 2024Safety, tolerability, and pharmacokinetics of a single orally inhaled dose of PUR3100, a dry powder formulation of dihydroergotamine versus intravenous dihydroergotamine: A Phase 1 randomized, double-blind study in healthy adults
Abstract Background: Intravenous dihydroergotamine (DHE) has well-established efficacy for the acute treatment of migraine, but its use is limited by the need for in-hospital administration and the nausea/vomiting associated with a high maximum plasma...
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May 10, 2024Investigating the causal association between systemic lupus erythematosus and migraine using Mendelian randomization analysis
Abstract Objective: To assess whether systemic lupus erythematosus (SLE) may be genetically causally associated with migraine, including the two primary subtypes: migraine with aura (MWA) and migraine without aura (MWoA). Background: The association between...
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May 3, 2024Virtual dynamic interaction games reveal impaired multisensory integration in women with migraine
Abstract Objective: In this cross-sectional observational study, we aimed to investigate sensory profiles and multisensory integration processes in women with migraine using virtual dynamic interaction systems. Background: Compared to studies on unimodal sensory processing,...
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May 3, 2024The impact of the migraine treatment onabotulinumtoxinA on inflammatory and pain responses: Insights from an animal model
Abstract Objective: Migraine, a prevalent and debilitating disease, involves complex pathophysiology possibly including inflammation and heightened pain sensitivity. The current study utilized the complete Freund’s adjuvant (CFA) model of inflammation, with onabotulinumtoxinA (BoNT/A) as...
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May 3, 2024Prevalence and burden of migraine in the United States: A systematic review
Abstract Background: This study reviewed migraine prevalence and disability gathered through epidemiologic survey studies in the United States conducted over the past three decades. We summarized these studies and evaluated changing patterns of disease...
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May 3, 2024Sequential administration of peripheral nerve blocks and onabotulinumtoxinA for the treatment of chronic migraine and other headache disorders-A retrospective tolerability and safety study
Abstract Objective: To determine the tolerability and safety of concurrent peripheral nerve blocks and onabotulinumtoxinA treatment during a single outpatient clinic procedure visit. Background: Procedural interventions are available for the treatment of headache disorders....
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May 3, 2024A rare case of lupus cerebritis presenting as ictal epileptic headache: A case report
Abstract Ictal epileptic headache, characterized by headache as the sole symptom of a seizure attack, is a rare condition. In this case report, we present a 52-year-old female with a history of systemic lupus...
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May 3, 2024Association between migraine and exclusive breastfeeding: A cross-sectional study
Abstract Background: Medical conditions may preclude a mother from exclusively breastfeeding her infant; however, the association between migraine and the duration of exclusive breastfeeding is not well known. Objective: To evaluate the association between...
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April 26, 2024The effectiveness of parenteral agents for pain reduction in patients with migraine presenting to emergency settings: A systematic review and network analysis
Abstract Objectives: To assess the comparative effectiveness and safety of parenteral agents for pain reduction in patients with acute migraine. Background: Parenteral agents have been shown to be effective in treating acute migraine pain;...
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April 26, 2024Challenges in the management of new daily persistent headache at a tertiary headache center-A retrospective real-world evidence study
Abstract Objective: In this retrospective cross-sectional real-world evidence study from the Danish Headache Center (DHC), a national tertiary headache center in Denmark, we sought to identify potential pharmacological agents for the treatment of new...
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April 26, 2024Implications of high homocysteine levels in migraine pain: An experimental study of the excitability of peripheral meningeal afferents in rats with hyperhomocysteinemia
Abstract Objectives: Investigation of chronic homocysteine action on the excitability and N-methyl-D-aspartate (NMDA) sensitivity of the peripheral trigeminovascular system of rats. Background: Migraine is a neurological disease that affects 15%-20% of the general population....
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April 26, 2024Reliability, validity, and responsiveness of the Arabic version of HIT-6 questionnaire in patients with migraine indicated for preventive therapy: A multi-center study
Abstract Background: The Headache Impact Test (HIT-6) is an important patient-reported outcome measure (PROM) in migraine prevention trials. Objectives: This study aimed to (i) assess the reliability and validity of the Arabic version of...
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April 26, 2024Blood serum levels of PACAP and migraine onset: A systematic review and meta-analysis of observational studies
Abstract Objective: We conducted a systematic review and meta-analysis to explore the relationship between blood pituitary adenylate cyclase-activating polypeptide (PACAP) levels and migraine. Background: PACAP is involved in the onset of migraine, but the...
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April 26, 2024Progressive superficial siderosis despite complete remission of intracranial hypotension symptoms following epidural patching: Case report
Abstract Spontaneous intracranial hypotension (SIH) commonly results from ventral spinal cerebrospinal fluid (CSF) leaks and epidural patches are advocated as first-line treatment. Complications such as superficial siderosis can arise but have previously been reported...
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April 19, 2024Nonspecific oral medications versus anti-calcitonin gene-related peptide monoclonal antibodies for migraine: A systematic review and meta-analysis of randomized controlled trials
Abstract Objective: To compare calcitonin gene-related peptide monoclonal antibodies (CGRP mAbs) versus nonspecific oral migraine preventives (NOEPs). Background: Insurers mandate step therapy with NOEPs before approving CGRP mAbs. Methods: Databases were searched for class...
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April 19, 2024Depression and anxiety are not associated with migraine outcomes in children and adolescents
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April 19, 2024
