1101 Results found
Articles
Virtual issue: Education in headache medicine: Insights and advancements from 2023 to 2024
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July 11, 2025Intracranial hypertension with papilledema associated with long-term use of over-the-counter retinol day cream
No abstract available Keywords: hypervitaminosis A; intracranial hypertension; papilledema.
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July 11, 2025A 52-week open-label extension study to evaluate the safety and efficacy of oral rimegepant for the preventive treatment of migraine
Abstract Objective: To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52-week, open-label extension (OLE) study. Background: Rimegepant...
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July 4, 2025Efficacy and safety of rimegepant for the acute treatment of migraine in Japan: A dose-ranging, double-blind, randomized controlled trial
Abstract Objective: The objectives of this study were to compare the efficacy, including dose response, and safety of rimegepant, an orally administered small-molecule calcitonin gene-related peptide receptor antagonist, with placebo for the acute treatment...
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July 4, 2025Underdiagnosis and impact of menstrual migraine in real-world clinical practice: A real-world survey
Abstract Objective: This cross-sectional study aimed to evaluate the frequency of menstrual migraine (MM) reporting in clinical practice and to compare the clinical burden, treatment patterns, and patient satisfaction between those with and without...
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July 4, 2025Greater occipital nerve block for chronic headache management in children and adolescents: A longitudinal observational study and systematic review
Abstract Objectives/background: Treatment options for children and adolescents with chronic headache are limited. Greater occipital nerve block (GONB) has been shown to be effective in headache relief in adults, with minimal side effects, whereas...
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July 4, 2025Prevalence of adverse childhood experiences in the refractory chronic migraine population compared to non-refractory chronic and episodic migraine
Abstract Objective: To analyze adverse childhood experiences (ACEs) scores, headache frequency, and disability (six-item Headache Impact Test , Migraine Disability Assessment Scale ) in individuals with refractory chronic migraine (rCM) recommended for inpatient infusion...
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June 27, 2025Efficacy and safety of rimegepant for the preventive treatment of migraine in Japan: A double-blind, randomized controlled trial
Abstract Objectives/background: This study was undertaken to compare the efficacy of the oral calcitonin gene-related peptide receptor antagonist rimegepant relative to placebo as a preventive treatment for migraine in Japan. This was the first...
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June 27, 2025Cardiovascular risk and triptan usage among patients with migraine
Abstract Background: Migraine, a neurovascular disorder evident by recurrent headaches, is associated with increased risk of ischemic vascular events, including ischemic stroke and myocardial infarction. Triptans, acute migraine-specific treatment, cause vasoconstriction, complicating treatment decisions,...
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June 27, 2025Patient preferences for the preventive treatment of episodic migraine in the United States: A discrete-choice experiment
Abstract Objectives: This study was conducted among participants with episodic migraine, to (i) assess patient preferences for attributes associated with calcitonin gene-related peptide-targeting therapies to prevent migraine and (ii) predict the probability that a...
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June 27, 2025Reassessing pediatric migraine disability: Toward an updated assessment tool in the era of novel therapeutics
No abstract available Keywords: PedMIDAS; migraine disorders; psychiatric comorbidities.
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June 27, 2025Early nimodipine treatment in reversible cerebral vasoconstriction syndrome: A serial transcranial Doppler study
Abstract Objectives/background: Although nimodipine is commonly used to treat reversible cerebral vasoconstriction syndrome (RCVS), its disease-modifying effects are not yet understood. We prospectively investigated the effect of nimodipine and treatment initiation timing on the...
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June 27, 2025Characterizing sleep, headache-related disability, and psychological functioning among adolescents with continuous headache: A pilot study from a tertiary clinical setting
Abstract Objectives/background: Youth with continuous headache are understudied, are presumed to be more psychosocially complex and impaired than youth with remitting headache presentations, and are at risk for poor clinical outcomes. Given links between...
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June 20, 2025Effectiveness and tolerability of liraglutide as add-on treatment in patients with obesity and high-frequency or chronic migraine: A prospective pilot study
Abstract Objective: To assess whether glucagon-like-peptide-1 receptor (GLP-1R) agonists could serve as a novel prophylactic treatment for migraine in patients with obesity. Background: Increased intracranial pressure (ICP) is speculated to play a role in...
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June 20, 2025Identifying cognitive-affective mechanisms underlying disability in episodic migraine: Using the fear avoidance model to examine interactions
Abstract Objective: Using the fear-avoidance model (FAM) as a theoretical framework, this study examined the interactions between empirical factors contributing to disability in episodic migraine. It was tested whether pain catastrophizing, fear of attacks,...
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June 20, 2025Regulation of Na+, K+-ATPase by cardiotonic steroids: Participation in the sodium theory for migraine
Abstract Background: The sodium theory for migraine proposes that excessive sodium pumping into the cerebrospinal fluid (CSF) leads to sodium infiltration into the neural tissue, which can lead to activation and central sensitization of...
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June 20, 2025Combination behavioral and pharmacological interventions through telehealth platforms: Opportunities for increasing access and optimizing migraine outcomes
No abstract available Keywords: acceptance and commitment therapy; behavioral therapy; calcitonin gene‐related peptide; migraine.
Published:
June 20, 2025
