Intrathecal Neurolysis

This powerful presentation explores the role of intrathecal neurolysis in managing refractory cancer pain in palliative care. Highlighting that 30% of cancer patients do not respond to standard multimodal analgesia, Dr. Perez Moreno advocates for chemical neurolysis—primarily using alcohol or phenol—to achieve meaningful relief. Detailed comparisons between aqueous and glycerinated phenol and alcohol reveal their chemical behaviors, densities, and risk profiles. Through compelling clinical cases, including terminal patients requesting euthanasia due to unbearable pain, Dr. Perez Moreno demonstrates how carefully executed intrathecal neurolysis can offer dramatic pain relief, preserve dignity, and avoid motor complications, reinforcing its value as a compassionate, evidence-informed intervention.