1413 Results found
Articles
A Lesson in Loss: A Novice Anesthesiologist’s Journey
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AnesthesiologyPublished:
April 26, 2024Discovering the Intriguing Properties of Extrasynaptic γ-Aminobutyric Acid Type A Receptors
Abstract Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors. By Caraiscos VB, Elliott EM, You-Ten KE, Cheng VY, Belelli D, Newell JG, Jackson MF,...
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AnesthesiologyPublished:
April 26, 2024Effects of positive end-expiratory pressure on pulmonary perfusion distribution and intrapulmonary shunt during one-lung ventilation in pigs A randomized crossover study
Abstract Background: During one-lung ventilation (OLV), positive end-expiratory pressure (PEEP) can improve lung aeration, but might over-distend lung units and increase intrapulmonary shunt. We hypothesized that higher PEEP shifts pulmonary perfusion from the ventilated...
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AnesthesiologyPublished:
April 26, 2024Activity of the sodium leak channel maintains the excitability of paraventricular thalamus glutamatergic neurons to resist anesthetic effects of sevoflurane in mice
Abstract Background: Stimulation of the paraventricular thalamus has been found to enhance anesthesia recovery; however, the underlying molecular mechanism by which general anesthetics modulate paraventricular thalamus is unclear. Here, we aimed to test the...
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AnesthesiologyPublished:
April 26, 2024Association between Colonoscopy Sedation Type and Polyp Detection: A Registry-based Cohort Study
Abstract Background: Colorectal cancer is a leading cause of cancer-related death. Adenomas and serrated polyps are precursors of colorectal cancer, with serrated polyps being more difficult to detect during colonoscopy. The relationship between propofol...
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AnesthesiologyPublished:
April 26, 2024Does Propofol Improve Polyp Detection during Colonoscopy? The Promise and Peril of Clinical Registry Data
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AnesthesiologyPublished:
April 26, 2024Meta-analyses of Randomized Clinical Trials in Postsurgical Pain: Verify before Trusting: Erratum
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AnesthesiologyPublished:
April 26, 2024Global and regional heterogeneity of lung aeration in neonates with different respiratory disorders: a physiological, observational study
Abstract Background.: Aeration heterogeneity affects lung stress and influences outcomes in adults with acute respiratory distress syndrome (ARDS). We hypothesize that aeration heterogeneity may differ between neonatal respiratory disorders and is associated with oxygenation,...
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AnesthesiologyPublished:
April 26, 2024Safety and Efficacy of Vocacapsaicin for Management of Postsurgical Pain: A Randomized Clinical Trial
Abstract Background: Nonopioid management of postsurgical pain remains a major unmet need. Few studies have evaluated TRPV1 agonists for analgesia after surgery. We studied intraoperative vocacapsaicin, a novel prodrug of the TRPV1 agonist capsaicin,...
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AnesthesiologyPublished:
April 26, 2024Incidence and risk factors of chronic postoperative pain in same-day surgery: A prospective cohort study
Abstract Background: The amount of same-day surgery has increased markedly worldwide in recent decades, but there remains limited evidence on chronic postsurgical pain in this setting. Methods: We assessed pain 90 days after ambulatory...
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AnesthesiologyPublished:
April 26, 2024Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial
Abstract Background: More than 500,000 elective tonsillectomies are performed in US children annually. Pain after pediatric tonsillectomy is common, often severe, and undertreated. There is no consensus on the optimal management of perioperative tonsillectomy...
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AnesthesiologyPublished:
April 26, 2024Novel Resuscitation Strategies in Severe Trauma: Reply
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AnesthesiologyPublished:
April 12, 2024Novel Resuscitation Strategies in Severe Trauma: Comment
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AnesthesiologyPublished:
April 12, 2024American Society of Anesthesiologists 2023 Guidance on Neurologic Complications of Neuraxial Analgesia/Anesthesia in Obstetrics
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AnesthesiologyPublished:
April 12, 2024Cortical Dynamics and Postoperative Cognition: Comment
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AnesthesiologyPublished:
April 12, 2024Cortical Dynamics and Postoperative Cognition: Reply
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AnesthesiologyPublished:
April 12, 2024
