Visceral Neurolytic Blocks for Cancer Pain

This presentation addresses cancer-related abdominal and pelvic pain management through interventional procedures targeting sympathetic pathways.

Visceral Neurolytic Blocks for Cancer Pain

Published on October 22, 2025

This presentation addresses cancer-related abdominal and pelvic pain management through interventional procedures targeting sympathetic pathways.

Dr. Ale reviews indications for splenic nerve neurolysis and celiac plexus block, especially for upper abdominal malignancies like pancreatic cancer. Current evidence supports these blocks (graded 2B+) for opioid-sparing analgesia, though high-quality studies are limited. Advances include CT-guided and endoscopic approaches, and adjunct use of agents like dexmedetomidine to enhance outcomes. The talk also covers superior hypogastric plexus neurolysis for refractory pelvic pain, detailing approaches, complications, and preventive measures. Emphasis is placed on early integration of these procedures and the need for better evidence to improve cancer pain care.

Description

This presentation addresses cancer-related abdominal and pelvic pain management through interventional procedures targeting sympathetic pathways.

Dr. Ale reviews indications for splenic nerve neurolysis and celiac plexus block, especially for upper abdominal malignancies like pancreatic cancer. Current evidence supports these blocks (graded 2B+) for opioid-sparing analgesia, though high-quality studies are limited. Advances include CT-guided and endoscopic approaches, and adjunct use of agents like dexmedetomidine to enhance outcomes. The talk also covers superior hypogastric plexus neurolysis for refractory pelvic pain, detailing approaches, complications, and preventive measures. Emphasis is placed on early integration of these procedures and the need for better evidence to improve cancer pain care.

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