Finding the Connection Between Innovation

This presentation offers an insightful overview of the current landscape and investment trends in pain neuromodulation, spanning implantable and non-invasive technologies. While spinal cord stimulation (SCS) remains dominant by market share, diverse approaches such as PNS, TMS, ultrasound, and optogenetics are gaining attention.

Finding the Connection Between Innovation

Published on August 25, 2025

This presentation offers an insightful overview of the current landscape and investment trends in pain neuromodulation, spanning implantable and non-invasive technologies. While spinal cord stimulation (SCS) remains dominant by market share, diverse approaches such as PNS, TMS, ultrasound, and optogenetics are gaining attention. Dr. Jeremy Koff highlights the key drivers for successful innovation—capital, team, and execution—over just technology. He outlines investment considerations, funding trends, and real-world examples from recent IPOs and acquisitions. Despite market volatility, investor interest is rebounding, especially for companies with compelling clinical value and strong commercialization strategies.

Description

This presentation offers an insightful overview of the current landscape and investment trends in pain neuromodulation, spanning implantable and non-invasive technologies. While spinal cord stimulation (SCS) remains dominant by market share, diverse approaches such as PNS, TMS, ultrasound, and optogenetics are gaining attention. Dr. Jeremy Koff highlights the key drivers for successful innovation—capital, team, and execution—over just technology. He outlines investment considerations, funding trends, and real-world examples from recent IPOs and acquisitions. Despite market volatility, investor interest is rebounding, especially for companies with compelling clinical value and strong commercialization strategies.

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