Does evidence show that neurolysis is effective? In this lecture, Ludger Gerdesmeyer, MD, PhD, FIPP, presents results from a clinical trial that showcase the potential benefits of epidural adhesiolysis. He also advocates for the use of evidence-based medicine, discusses his surprising placebo results, and explains the biases and flaws of past trial designs that tried to answer this question. This lecture was filmed at the 24th Annual Gabor Racz Pain Conference and Workshop.