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Activation Principles of Platelet Rich Plasma

Dr. Singh has been attending the NYNJ Pain Congress for over a decade and presented a compelling talk on platelet-rich plasma (PRP) activation and its role in regenerative medicine. Initially skeptical, his research at Weill Cornell Medicine revealed consistent functional and pain improvements in patients—even when imaging didn’t change—prompting deeper investigation into PRP dosing, growth factor release, and activation methods (calcium chloride, thrombin, freeze/thaw). He emphasized the importance of measuring platelet counts, tailoring therapy by indication, and advancing the field through standardized reporting (PLRA). His call to action: collaborate, count, and focus on patient outcomes—not just imaging.

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(L) Dr. Juan Miguel Jimenez Andrade – New Concept Otheogenic Pain – Video Hero Slider

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New Concept Osteogenic Pain

This talk explores osteogenic pain—pain originating from bone tissue—and credits Dr. Plancarte for introducing the concept. Dr. Jimenez Andrade traces the historical view of bone as merely structural, highlighting new evidence showing that bone is richly innervated, particularly with peptidergic sensory fibers, unlike skin, which has both peptidergic and non-peptidergic fibers. Using animal models of fracture and cancer, the team demonstrates that blocking the NGF/TRK pathway leads to analgesic effects. Human studies confirm similar nerve remodeling in bone metastases. The findings support a paradigm shift: bone is a distinct pain source with unique nerve characteristics, offering new therapeutic targets.

Minimally Invasive Procedures for Central and Neuroforaminal Spinal Stenosis

Dr. Steve Aydin reflects on the evolution of minimally invasive treatments for lumbar spinal stenosis, questioning whether these procedures truly change patient outcomes or mainly improve symptoms. He compares options like MILD (percutaneous lumbar decompression) and interspinous devices (Vertiflex, Minuteman), noting that while imaging rarely shows significant post-procedure change, patients often experience relief. The talk highlights challenges in patient selection, balancing risks like facet pain after spacers, and the importance of individualized algorithms for central versus foraminal stenosis. Aiden emphasizes adaptability as techniques evolve, aiming for the least invasive intervention with meaningful symptom improvement over aggressive surgical alternatives.

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Intrathecal Neurolysis

This powerful presentation explores the role of intrathecal neurolysis in managing refractory cancer pain in palliative care. Highlighting that 30% of cancer patients do not respond to standard multimodal analgesia, Dr. Perez Moreno advocates for chemical neurolysis—primarily using alcohol or phenol—to achieve meaningful relief. Detailed comparisons between aqueous and glycerinated phenol and alcohol reveal their chemical behaviors, densities, and risk profiles. Through compelling clinical cases, including terminal patients requesting euthanasia due to unbearable pain, Dr. Perez Moreno demonstrates how carefully executed intrathecal neurolysis can offer dramatic pain relief, preserve dignity, and avoid motor complications, reinforcing its value as a compassionate, evidence-informed intervention.

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(L) Dr. Baher Yanni – Posterolateral Mis Fusion for Degenerative Instability – Video Hero Slider

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This presentation explores lumbar spinal stenosis and the evolution of minimally invasive treatments, focusing on fusion techniques for patients with instability. The speaker reviews the stages of spinal stenosis, common symptoms like neurogenic claudication, and current interventions including MILD, Vertiflex, and interspinous fixation devices. While mild and Vertiflex address decompression, they lack stability for advanced cases. The discussion emphasizes posterolateral minimally invasive fusion with devices such as Minuteman, which restore alignment, lift disc height, and achieve standalone fixation with reduced tissue damage and lower infection risk. Clinical cases and biomechanical data demonstrate improved fusion rates, pain reduction, and functional outcomes.

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Posterolateral Mis Fusion for Degenerative Instability

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Activation Principles of Platelet Rich Plasma

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New Concept Osteogenic Pain

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Minimally Invasive Procedures for Central and Neuroforaminal Spinal Stenosis

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Intrathecal Neurolysis

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Posterolateral Mis Fusion for Degenerative Instability

This presentation explores lumbar spinal stenosis and the evolution of minimally invasive treatments, focusing on fusion techniques for patients with instability. Dr. Baher Yanni reviews the stages of spinal stenosis, common symptoms like neurogenic claudication, and current interventions including MILD, Vertiflex, and interspinous fixation devices. While mild and Vertiflex address decompression, they lack stability for advanced cases. The discussion emphasizes posterolateral minimally invasive fusion with devices such as Minuteman, which restore alignment, lift disc height, and achieve standalone fixation with reduced tissue damage and lower infection risk. Clinical cases and biomechanical data demonstrate improved fusion rates, pain reduction, and functional outcomes.

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Annu Navani

January 10, 2019

Published on January 10, 2019 Dr. Annu Navani demonstrates how to perform sacroiliac injections in a cadaver lab. She first details the anatomy of the SI joint, and explains why injections are done in the...

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Annu Navani

August 2, 2017

Evolution of Regenerative Medicine in Musculoskeletal and Lumbar Spine Disorders

Dr. Annu Navani gives a slide presentation on the application of regenerative medicine for musculoskeletal and spine pathologies.

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Annu Navani

June 13, 2017

Regenerative Medicine

Dr. Annu Navani discusses the use of regenerative medicine.

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Evolution of Regenerative Medicine in Musculoskeletal and Lumbar Spine Disorders

Regenerative Medicine

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