All Videos – PainCast

(L) Chris Gilligan – Multi-Center Prospective Cohort of Intractable Chronic Low Back Pain Treated with Restorative Neurostimulation – Video Hero Slider

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This presentation reviews the REACTIV8-B trial, a five-year study on restorative neurostimulation targeting L2 medial branch nerves to restore multifidus muscle function for chronic low back pain. Conducted across 26 global centers, the trial included patients with severe, refractory pain who failed conventional therapies. Results: pain scores improved from 7.3 to 2.4, Oswestry Disability Index dropped from 39 to 16, and health-related quality of life normalized. 46% eliminated opioids, and no lead migrations occurred. Unique findings include patients explanted due to cure and long-term durability without tolerance. Real-world outcomes mirror trial results, reinforcing this as a disease-modifying therapy for functional spine stability.

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Multi-Center Prospective Cohort of Intractable Chronic Low Back Pain Treated with Restorative Neurostimulation

(L) Dr. Jaspal Ricky Singh – Activation Principles of Platelet Rich Plasma – Video Hero Slider

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Activation Principles of Platelet Rich Plasma

Dr. Singh has been attending the NYNJ Pain Congress for over a decade and presented a compelling talk on platelet-rich plasma (PRP) activation and its role in regenerative medicine. Initially skeptical, his research at Weill Cornell Medicine revealed consistent functional and pain improvements in patients—even when imaging didn’t change—prompting deeper investigation into PRP dosing, growth factor release, and activation methods (calcium chloride, thrombin, freeze/thaw). He emphasized the importance of measuring platelet counts, tailoring therapy by indication, and advancing the field through standardized reporting (PLRA). His call to action: collaborate, count, and focus on patient outcomes—not just imaging.

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(L) Dr. Juan Miguel Jimenez Andrade – New Concept Otheogenic Pain – Video Hero Slider

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New Concept Osteogenic Pain

This talk explores osteogenic pain—pain originating from bone tissue—and credits Dr. Plancarte for introducing the concept. Dr. Jimenez Andrade traces the historical view of bone as merely structural, highlighting new evidence showing that bone is richly innervated, particularly with peptidergic sensory fibers, unlike skin, which has both peptidergic and non-peptidergic fibers. Using animal models of fracture and cancer, the team demonstrates that blocking the NGF/TRK pathway leads to analgesic effects. Human studies confirm similar nerve remodeling in bone metastases. The findings support a paradigm shift: bone is a distinct pain source with unique nerve characteristics, offering new therapeutic targets.

(L) Dr. Steve Aydin – Minimally Invasive Procedures for Central and Neuroforaminal Spinal Stenosis – Video Hero Slider

Minimally Invasive Procedures for Central and Neuroforaminal Spinal Stenosis

Dr. Steve Aydin reflects on the evolution of minimally invasive treatments for lumbar spinal stenosis, questioning whether these procedures truly change patient outcomes or mainly improve symptoms. He compares options like MILD (percutaneous lumbar decompression) and interspinous devices (Vertiflex, Minuteman), noting that while imaging rarely shows significant post-procedure change, patients often experience relief. The talk highlights challenges in patient selection, balancing risks like facet pain after spacers, and the importance of individualized algorithms for central versus foraminal stenosis. Aiden emphasizes adaptability as techniques evolve, aiming for the least invasive intervention with meaningful symptom improvement over aggressive surgical alternatives.

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(L) Dr. Diana Perez Moreno_ Intrathecal Neurolysis – Video Hero Slider

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Intrathecal Neurolysis

This powerful presentation explores the role of intrathecal neurolysis in managing refractory cancer pain in palliative care. Highlighting that 30% of cancer patients do not respond to standard multimodal analgesia, Dr. Perez Moreno advocates for chemical neurolysis—primarily using alcohol or phenol—to achieve meaningful relief. Detailed comparisons between aqueous and glycerinated phenol and alcohol reveal their chemical behaviors, densities, and risk profiles. Through compelling clinical cases, including terminal patients requesting euthanasia due to unbearable pain, Dr. Perez Moreno demonstrates how carefully executed intrathecal neurolysis can offer dramatic pain relief, preserve dignity, and avoid motor complications, reinforcing its value as a compassionate, evidence-informed intervention.

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Slide

Multi-Center Prospective Cohort of Intractable Chronic Low Back Pain Treated with Restorative Neurostimulation

This presentation reviews the REACTIV8-B trial, a five-year study on restorative neurostimulation targeting L2 medial branch nerves to restore multifidus muscle function for chronic low back pain. Conducted across 26 global centers, the trial included patients with severe, refractory pain who failed conventional therapies. Results: pain scores improved from 7.3 to 2.4, Oswestry Disability Index dropped from 39 to 16, and health-related quality of life normalized. 46% eliminated opioids, and no lead migrations occurred. Unique findings include patients explanted due to cure and long-term durability without tolerance. Real-world outcomes mirror trial results, reinforcing this as a disease-modifying therapy for functional spine stability.

Slide

Dr. Singh has been attending the NYNJ Pain Congress for over a decade and presented a compelling talk on platelet-rich plasma (PRP) activation and its role in regenerative medicine. Initially skeptical, his research at Weill Cornell Medicine revealed consistent functional and pain improvements in patients—even when imaging didn’t change—prompting deeper investigation into PRP dosing, growth factor release, and activation methods (calcium chloride, thrombin, freeze/thaw). He emphasized the importance of measuring platelet counts, tailoring therapy by indication, and advancing the field through standardized reporting (PLRA). His call to action: collaborate, count, and focus on patient outcomes—not just imaging.

Activation Principles of Platelet Rich Plasma

Slide

This talk explores osteogenic pain—pain originating from bone tissue—and credits Dr. Plancarte for introducing the concept. Dr. Jimenez Andrade traces the historical view of bone as merely structural, highlighting new evidence showing that bone is richly innervated, particularly with peptidergic sensory fibers, unlike skin, which has both peptidergic and non-peptidergic fibers. Using animal models of fracture and cancer, the team demonstrates that blocking the NGF/TRK pathway leads to analgesic effects. Human studies confirm similar nerve remodeling in bone metastases. The findings support a paradigm shift: bone is a distinct pain source with unique nerve characteristics, offering new therapeutic targets.

New Concept Osteogenic Pain

Slide

Dr. Steve Aydin reflects on the evolution of minimally invasive treatments for lumbar spinal stenosis, questioning whether these procedures truly change patient outcomes or mainly improve symptoms. He compares options like MILD (percutaneous lumbar decompression) and interspinous devices (Vertiflex, Minuteman), noting that while imaging rarely shows significant post-procedure change, patients often experience relief. The talk highlights challenges in patient selection, balancing risks like facet pain after spacers, and the importance of individualized algorithms for central versus foraminal stenosis. Aiden emphasizes adaptability as techniques evolve, aiming for the least invasive intervention with meaningful symptom improvement over aggressive surgical alternatives.

Minimally Invasive Procedures for Central and Neuroforaminal Spinal Stenosis

Slide

This powerful presentation explores the role of intrathecal neurolysis in managing refractory cancer pain in palliative care. Highlighting that 30% of cancer patients do not respond to standard multimodal analgesia, Dr. Perez Moreno advocates for chemical neurolysis—primarily using alcohol or phenol—to achieve meaningful relief. Detailed comparisons between aqueous and glycerinated phenol and alcohol reveal their chemical behaviors, densities, and risk profiles. Through compelling clinical cases, including terminal patients requesting euthanasia due to unbearable pain, Dr. Perez Moreno demonstrates how carefully executed intrathecal neurolysis can offer dramatic pain relief, preserve dignity, and avoid motor complications, reinforcing its value as a compassionate, evidence-informed intervention.

Intrathecal Neurolysis

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Videos

Harold J. Cordner

October 26, 2018

Published on October 26, 2018 Dr. Harold Cordner discusses the pathogenesis of lumbar spinal stenosis. He explains how the narrowing of the spinal canal and foramina can irritate spinal nerves with extension. He shows how...

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Harold Cordner

...+1

October 19, 2018

Published on October 19,2018 Dr. Harold Cordner demonstrates a two-needle technique for a lumbar discogram. By using an introducer, he explains, the needle entering the disc does not come in contact with the skin’s normal...

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Harold Cordner

...+1

July 27, 2018

Published on July 27, 2018 Drs. Ricardo Buenaventura and Harold Cordner answer questions regarding the MILD procedure from an audience of physicians. Topics discussed include the number of stenotic segments can be treated per procedure,...

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Harold Cordner

...+1

May 18, 2014

Spinal Cord Stimulation: The Benefits of Conventional vs. High Frequency

Dr. Harold Cordner talks about spinal cord stimulation and newer technologies, such as conventional and high frequency stimulation.

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