How can we use biologics to treat lower back pain? Dr. Aaron Calodney describes the biological processes that underlie back health and explains how homeostasis can be disrupted or restored. By using autologous transplants containing various stem and progenitor cells, growth factors, and platelets, the underlying causes of back pain can be reversed. Dr. Calodney describes how these therapies can directly target biological mechanisms and summarizes their safety and efficacy in clinical trials.