New Concept Osteogenic Pain

This presentation introduces the concept of osteogenic pain, emphasizing that bone is more than a structural tissue—it is richly innervated with nociceptive fibers, making it a significant pain generator. Evidence from human and animal studies shows dense sensory innervation in bone, similar to skin, involving C fibers. Conditions such as metastasis, fractures, and osteoedema can disturb this nociceptive system. Clinical implications include minimally invasive strategies like polymethylmethacrylate (PMMA) applications, vertebral stabilization, and combined approaches (e.g., RF ablation with PMMA) to reduce pain and enhance stability. The talk calls for further research and the adoption of new diagnostic and therapeutic methods for bone pain.