Gupta – Neuromodulation and Neuroplasticity

Dr. Gupta addresses the challenge of habituation in neuromodulation therapy for chronic pain patients. Habituation leads to a decrease in efficacy over time despite the initial success. He discusses various studies highlighting strategies to mitigate habituation, including low-dose and microdosing approaches, pulse dosing, alternating waveforms, and stimulation holidays. These methods aim to maintain therapeutic efficacy and delay habituation. The emphasis is on personalized treatment plans that adapt to the patient’s needs to sustain long-term pain relief and improve patient outcomes in neuromodulation therapy.